CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15328
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand AGN-PC-001WPY family
No. of Seeds 12 No. of Other Members 3
Family Centroid CFAMM00433450 Functional Category Bioactive
Superfamily GABA theta subunit and Gamma-aminobutyric acid receptor subunit pi Binder Superfamily 7
Class Class 1355

Cousin Family NamesSeedsMembers
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Aromatase Inhibitor NSC-356781 Family 3 10
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 5 58
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Ribosomal protein S6 kinase beta-1 and Rho-associated protein ... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 10 37
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 12
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 14
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 4 0
Smoothened homolog and Sonic hedgehog protein inhibitor N-cycl... 3 2
Ribosomal protein S6 kinase alpha-5 inhibitor AGN-PC-075HAD fa... 2 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Cathepsin K inhibitor SureCN4141224 family 3 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433459 CHEMBL308359 Bioactive AGN-PC-001WPI
CFAMM00433458 CHEMBL75104 Bioactive AGN-PC-001WPU
CFAMM00433450 CHEMBL305704 Bioactive AGN-PC-001WPY
CFAMM00433457 CHEMBL308265 Bioactive AGN-PC-001WPT
CFAMM00433449 CHEMBL306088 Bioactive AGN-PC-001WPW
CFAMM00433462 CHEMBL307819 Bioactive AGN-PC-001WPQ
CFAMM00433454 CHEMBL306342 Bioactive AGN-PC-001WQ2
CFAMM00433447 CHEMBL307836 Bioactive AGN-PC-001WQ5
CFAMM00433461 CHEMBL73457 Bioactive AGN-PC-001WQ3
CFAMM00433453 CHEMBL74452 Bioactive AGN-PC-001WPS
CFAMM00433460 CHEMBL74162 Bioactive AGN-PC-001WPX
CFAMM00433452 CHEMBL76465 Bioactive AGN-PC-001WQ4

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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