CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15333
Family Name Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00433480 Functional Category Bioactive
Superfamily Trypsin-1 and Prothrombin Binder Superfamily 4
Class Class 224

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 15 28
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinoli... 6 15
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 3 5
Disintegrin and metalloproteinase domain-containing protein 17... 8 0
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Dipeptidyl peptidase 4 inhibitor 2-[3-(aminomethyl)-4-(4-fluor... 3 0
DNA polymerase beta and Microtubule-associated protein tau inh... 1 1
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433480 CHEMBL75255 Bioactive AGN-PC-074I4I
CFAMM00433482 CHEMBL305811 Bioactive ethyl 2-[2-(4-carbamimidoylphenoxy)-4-methylquinolin-7-yl]butanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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