CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15345
Family Name Coagulation factor X inhibitor ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(benzylsulfonylamino)-5-(diaminomethylideneamino)pentanoyl]-methylamino]acetyl]amino]-2-oxo-4-phenylbutanoyl]amino]acetate family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00433570 Functional Category Bioactive
Superfamily Vasopressin V1a receptor Ligand Felypressin Superfamily
Class Class 168

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Prothrombin Inhibitor Efegatran Family 9 47
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor Ppack Family 5 4
Neuromedin-K receptor Ligand Senktide Family 15 22
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Nociceptin receptor Ligand Fggftgcrkscrk Family 10 0
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Melanocortin receptor 4 and Substance-K receptor Ligand Hoo-ph... 3 19
Cruzipain Inhibitor K-777 Family 3 8
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Trypsin Inhibitor P1 Argininal Derivative Family 13 36
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin and Suppressor of tumorigenicity 14 protein inhibi... 5 8
Prothrombin inhibitor SureCN7341151 family 6 7
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 8
Prothrombin inhibitor (2S)-N-[4-(2-amino-2-iminoethyl)cyclohex... 2 0
Trypsin-1 and Urokinase-type plasminogen activator inhibitor (... 3 9
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 0
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
Prothrombin and Coagulation factor X inhibitor tert-butyl (4R)... 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-(naphthalen-2... 3 1
Follicle-stimulating hormone receptor ligand N-[[3-[4-[[(2S,5S... 7 0
Prothrombin inhibitor methyl (3S)-3-[[(6S,8aS)-2-benzylsulfony... 5 1
Pepsin A and Renin inhibitor N-[(3R)-1-[[(1S)-1-hydroxy-3-[[(2... 1 0
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Cathepsin L1 inhibitor (2R)-2-[[3-benzylsulfanyl-2-[[2-(4-phen... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433571 CHEMBL75017 Bioactive (2R)-N-[2-[[(2S)-4-(benzylamino)-1-cyclohexyl-3,4-dioxobutan-2-yl]amino]-2-oxoethyl]-2-(benzylsulfonylamino)-5-(diaminomethylideneamino)-N-methylpentanamide
CFAMM00433570 CHEMBL309068 Bioactive ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(benzylsulfonylamino)-5-(diaminomethylideneamino)pentanoyl]-methylamino]acetyl]amino]-2-oxo-4-phenylbutanoyl]amino]acetate
CFAMM00433569 CHEMBL306309 Bioactive ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(benzylsulfonylamino)-5-(diaminomethylideneamino)pentanoyl]-methylamino]acetyl]amino]-4-cyclohexyl-2-oxobutanoyl]amino]acetate
CFAMM00433568 CHEMBL74418 Bioactive (2R)-2-(benzylsulfonylamino)-5-(diaminomethylideneamino)-N-[2-[[(2S)-3,4-dioxo-4-[[2-oxo-2-(2-phenylethylamino)ethyl]amino]-1-phenylbutan-2-yl]amino]-2-oxoethyl]-N-methylpentanamide;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543