CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15353
Family Name Tryptase alpha/beta-1 and Trypsin-1 inhibitor AGN-PC-074JFM family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00433624 Functional Category Bioactive
Superfamily Tryptase alpha/beta-1 and Trypsin-1 inhibitor AGN-PC-074JFM Superfamily
Class Class 5112

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
DNA Binder Procarbazine Family 8 358
Substance-P receptor Ligand Vestipitant Family 14 137
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Serine/threonine-protein kinase Chk1 Inhibitor 6-(3-aminopropy... 2 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Aminopeptidase N Inhibitor 2-amino-n1-benzyl-n3-hydroxymalonam... 3 4
Aminopeptidase N Inhibitor 2-benzyl-n1-hydroxy-n3-(4-phenylbut... 5 3
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 3
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-(cyanomethyl)-... 1 0
Histamine H3 receptor ligand 1-[[3-(4-piperidin-1-ylbut-1-ynyl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433624 CHEMBL76733 Bioactive AGN-PC-074JFM
CFAMM00433623 CHEMBL79822 Bioactive AGN-PC-074JFN
CFAMM00433622 CHEMBL306537 Bioactive AGN-PC-074JLV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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