CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15359
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]isoindole-1,3-dione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00274035 Functional Category Bioactive
Superfamily D(3) dopamine receptor and D(2) dopamine receptor Binder Superfamily 4
Class Class 1375

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Serum albumin Inhibitor Ebselen Family 3 62
Motilin receptor Ligand GSK962040 Family 30 457
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 19 88
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 15 24
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 6
Neuropeptide Y receptor type 2 ligand N-[3-chloro-4-[2-(cyclop... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 5
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 7 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 0
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
Testosterone 17-beta-dehydrogenase 3 inhibitor AGN-PC-00CHN2 f... 3 2
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-050YWL family 2 4
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
P2X purinoceptor 7 inhibitor SureCN3659568 family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Urotensin-2 receptor and Cytochrome P450 2D6 ligand 2-[3,4-dic... 2 3
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Muscarinic acetylcholine receptor M1 and Beta-lactamase ligand... 1 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 14 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Urotensin-2 receptor and Kappa-type opioid receptor ligand Sur... 2 0
Somatostatin receptor type 1 ligand AGN-PC-078XL4 family 2 0
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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