CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15377
Family Name Vasopressin V1a receptor and Vasopressin V2 receptor ligand AGN-PC-074IMM family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00132570 Functional Category Bioactive
Superfamily MK-3328 Superfamily
Class Class 681

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Glucokinase Inhibitor GKA1 Family 2 67
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 4 32
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
B2 bradykinin receptor Ligand FR-173657 Family 44 180
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 3
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
ALK tyrosine kinase receptor and Insulin receptor ligand SureC... 7 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0A9RFQ f... 2 1
Melatonin receptor type 1B ligand CHEMBL1802020 family 2 7
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Insulin-like growth factor 1 receptor and Potassium voltage-ga... 2 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 3 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 1... 1 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 3 1
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
ALK tyrosine kinase receptor ligand 4-fluoro-N-[1-[4-(propan-2... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Bifunctional epoxide hydrolase 2 inhibitor 8-(1H-benzimidazole... 1 0
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[1-(4-ethoxyp... 5 9
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Tyrosine-protein kinase Lck inhibitor SureCN374434 family 1 1
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 2 0
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Platelet-activating factor receptor ligand AGN-PC-00GDIY family 1 1
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 15 1
Hepatocyte growth factor receptor ligand 4-pyridone analogue, ... 8 0
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
Insulin-like growth factor 1 receptor ligand AGN-PC-050GPS family 7 0
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 6 0
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL4... 2 3
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 1
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8919280 f... 23 18


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543