CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15382
Family Name Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhibitor N-hydroxy-N-[1-hydroxy-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]formamide family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00433755 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 10
Class Class 4794

Cousin Family NamesSeedsMembers
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 5
Matrix metalloproteinase-9 inhibitor N-[1-[(4S)-2,2-dimethyl-1... 10 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
72 kDa type IV collagenase inhibitor N-hydroxy-N-[1-[4-[4-(tri... 3 2


External ID

Functional Category

Molecule Name

CFAMM00433759 CHEMBL77874 Bioactive N-hydroxy-N-[4-hydroxy-3-(hydroxymethyl)-1-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylbutan-2-yl]formamide
CFAMM00433758 CHEMBL75164 Bioactive N-[(3S)-3,4-dihydroxy-1-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylbutan-2-yl]-N-hydroxyformamide
CFAMM00433757 CHEMBL73866 Bioactive N-hydroxy-N-[1-methoxy-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]formamide
CFAMM00433756 CHEMBL309329 Bioactive N-hydroxy-N-[1-(2-hydroxyethoxy)-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]formamide
CFAMM00433755 CHEMBL307413 Bioactive N-hydroxy-N-[1-hydroxy-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]formamide
CFAMM00433754 CHEMBL74151 Bioactive N-hydroxy-N-[1-thiophen-2-ylsulfanyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]formamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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