CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15383
Family Name Coagulation factor X and Prothrombin inhibitor SureCN6434488 family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00433771 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366 Superfamily
Class Class 2628

Cousin Family NamesSeedsMembers
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 6 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Vascular endothelial growth factor receptor 2 ligand indolyl q... 4 3
Renin inhibitor SureCN1144364 family 3 15
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 17 4
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0759OR family 4 7
Beta-2 adrenergic receptor ligand SureCN5346426 family 8 0
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cannabinoid receptor 1 ligand (4-hydroxynaphthalen-1-yl)-[1-(2... 2 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... 2 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433771 CHEMBL307446 Bioactive SureCN6434488
CFAMM00433761 CHEMBL317811 Bioactive N,1-bis[(3-carbamimidoylphenyl)methyl]-4-hydroxyindole-2-carboxamide
CFAMM00433772 CHEMBL75544 Bioactive 1-[(3-carbamimidoylphenyl)methyl]-N-[(3,5-dichlorophenyl)methyl]-4-hydroxyindole-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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