CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1540
Family Name Epidermal growth factor receptor and Tyrosine-protein kinase ABL1 ligand AC1NS37K family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00192448 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit beta-1 and Gamma-aminobutyric acid receptor subunit alpha-1 Binder Superfamily
Class Class 3394

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Ibrutinib family 2 27
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Aurora kinase B and Tyrosine-protein kinase Lck Inhibitor CGP-... 2 29
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YMN ... 7 11
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Epidermal growth factor receptor and Cyclin-dependent kinase 1... 3 4
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
Proto-oncogene tyrosine-protein kinase Src and Phosphatidylino... 4 20
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Adenosine receptor A3 and Adenosine receptor A2a ligand 4-(5-b... 2 5
Tyrosine-protein kinase ABL1 and Tyrosine-protein kinase HCK i... 2 2
Tyrosine-protein kinase HCK and Proto-oncogene tyrosine-protei... 5 9
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Corticotropin-releasing factor receptor 1 ligand 5-N-(2-chloro... 7 1
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 1 0
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
Mitogen-activated protein kinase 14 inhibitor AGN-PC-075YQ1 fa... 4 0
Ribosomal protein S6 kinase beta-1 and RAC-alpha serine/threon... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 14 3
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 6
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2
Adenosine receptor A2a ligand AGN-PC-077RYF family 3 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WWHE family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324748 CHEMBL122182 Bioactive AC1NS36H
CFAMM00324747 CHEMBL331906 Bioactive AC1NS37E
CFAMM00324745 CHEMBL121954 Bioactive AC1NS36N

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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