CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15406
Family Name Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptamine receptor 2C ligand AGN-PC-07C08K family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00433884 Functional Category Bioactive with Natural Product
Superfamily Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 2035

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
Pitolisant family 4 24
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-... 2 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 2
Histamine H3 receptor ligand 4-[4-[4-(piperidin-1-ylmethyl)phe... 3 5
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
Sigma non-opioid intracellular receptor 1 and Kappa-type opioi... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433891 CHEMBL344422 Bioactive 1-benzyl-4-(cyclopropyloxymethyl)piperidine;(Z)-but-2-enedioic acid
CFAMM00433884 CHEMBL544847 Bioactive AGN-PC-07C08K

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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