CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15408
Family Name Histamine H3 receptor ligand AGN-PC-074FK2 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00433899 Functional Category Bioactive
Superfamily Interleukin-8 and Histamine H3 receptor Binder Superfamily
Class Class 3329

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Histamine H3 receptor Ligand SCH79687 Family 11 29
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 5 7
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Histamine H3 receptor ligand SureCN7853275 family 2 5
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 4
Histamine H3 receptor ligand AGN-PC-074FFM family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433901 CHEMBL420181 Bioactive AGN-PC-074FNA
CFAMM00433900 CHEMBL66438 Bioactive 4-chloro-N-[4-(1H-imidazol-5-yl)butyl]-N-methylbenzenesulfonamide
CFAMM00433899 CHEMBL69901 Bioactive AGN-PC-074FK2
CFAMM00433898 CHEMBL308244 Bioactive AGN-PC-074FIU

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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