CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15415
Family Name Tyrosine-protein kinase Lck inhibitor benzothiazole analog 11 family
No. of Seeds 7 No. of Other Members 13
Family Centroid CFAMM00433945 Functional Category Bioactive
Superfamily Tyrosine-protein kinase Lck Binder Superfamily
Class Class 888

Cousin Family NamesSeedsMembers
Abelson tyrosine-protein kinase 2 inhibitor thiazole derivativ... 19 50
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MPV family 4 0
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
D(2) dopamine receptor and Potassium voltage-gated channel sub... 2 0
Glycylpeptide N-tetradecanoyltransferase inhibitor AC1NRXA6 fa... 1 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-074FBQ family 2 0


External ID

Functional Category

Molecule Name

CFAMM00433945 CHEMBL67758 Bioactive benzothiazole analog 11
CFAMM00433957 CHEMBL68261 Bioactive AGN-PC-074FHB
CFAMM00433943 CHEMBL308432 Bioactive N-(2-chloro-6-methylphenyl)-2-[2-(1-methylpyrrolidin-2-yl)ethylcarbamoylamino]-1,3-benzothiazole-6-carboxamide
CFAMM00433948 CHEMBL68871 Bioactive AGN-PC-03SVJE
CFAMM00433954 CHEMBL309103 Bioactive AGN-PC-03SVK2
CFAMM00433952 CHEMBL68882 Bioactive AGN-PC-03SVG4

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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