CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15416
Family Name Epidermal growth factor receptor and Vascular endothelial growth factor receptor 1 ligand AGN-PC-074K4C family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00433962 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Vascular endothelial growth factor receptor 1 Binder Superfamily
Class Class 2909

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 53
Aurora kinase A Inhibitor ABT-348 Family 20 49
PF-3758309 family 1 8
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Epidermal growth factor receptor ligand AGN-PC-07C2E2 family 7 6
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
Metabotropic glutamate receptor 4 and Potassium voltage-gated ... 2 15
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
3-phosphoinositide-dependent protein kinase 1 and MAP kinase-a... 1 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 12 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
Epidermal growth factor receptor and Vascular endothelial grow... 14 19
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Epidermal growth factor receptor and Vascular endothelial grow... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433962 CHEMBL308498 Bioactive AGN-PC-074K4C
CFAMM00433964 CHEMBL312753 Bioactive AGN-PC-01VANR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27510 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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