CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15420
Family Name Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ligand SureCN7809164 family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00213534 Functional Category Bioactive with Natural Product
Superfamily Alpha-2A adrenergic receptor and Cytochrome P450 3A4 Binder Superfamily
Class Class 975

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 8
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Histamine H3 receptor Ligand Proxyfan Family 12 32
Nitric oxide synthase, inducible Inhibitor 4-(1h-imidazol-1-yl... 1 7
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 8
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 2
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 2 10
Histamine H3 receptor ligand AGN-PC-075YUJ family 2 0
Histamine H3 receptor ligand AGN-PC-075YXY family 1 4
D(2) dopamine receptor ligand AGN-PC-07C1V6 family 2 3
Glutaminyl-peptide cyclotransferase inhibitor 1-(3,4-dimethoxy... 1 17
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Putative NP ZINC32497112 Family 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433982 CHEMBL308570 Bioactive SureCN7808630
CFAMM00433981 CHEMBL432155 Bioactive SureCN7803545

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27283 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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