CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15434
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00382405 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 21
Class Class 1000

Cousin Family NamesSeedsMembers
Atrial natriuretic peptide receptor 1 Ligand Ataciguat Family 7 45
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
Coagulation factor X inhibitor AGN-PC-04YPWA family 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 7 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand 3-[... 18 26
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Coagulation factor X and Prothrombin inhibitor SureCN6592460 f... 14 1
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(p... 2 0
Coagulation factor X inhibitor SureCN14490781 family 15 0
Coagulation factor X inhibitor SureCN4855529 family 6 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Coagulation factor X inhibitor SureCN5432520 family 6 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Urotensin-2 receptor ligand 2-(5-chloro-1-benzothiophen-3-yl)-... 2 4
Adenosine receptor A1 ligand SureCN1497817 family 9 4
Muscarinic receptor 3 and Muscarinic acetylcholine receptor M2... 1 1
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434035 CHEMBL78800 Bioactive AGN-PC-074KCN
CFAMM00434033 CHEMBL78368 Bioactive AGN-PC-074KBG
CFAMM00434030 CHEMBL309727 Bioactive AGN-PC-074KGL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27627 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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