CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15435
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-PC-074KAV family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00330406 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Cellular tumor antigen p53 Binder Superfamily
Class Class 1000

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Propiomazine Family 4 10
Atrial natriuretic peptide receptor 1 Ligand Ataciguat Family 7 45
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Gonadotropin-releasing hormone receptor Ligand TAK-013 Family 19 10
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 1 14
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 7 1
Coagulation factor X inhibitor benzothiophene compound, 4 family 9 10
Thyroid hormone receptor beta and Cellular tumor antigen p53 l... 1 4
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Thyroid hormone receptor beta ligand CHEMBL1554195 family 1 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 0
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Coagulation factor X inhibitor AGN-PC-04YPWA family 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 7 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Coagulation factor X and Prothrombin inhibitor SureCN6592460 f... 14 1
5-hydroxytryptamine receptor 7 ligand 2a-[4-(6,7-dihydro-4H-th... 4 1
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Transient receptor potential M8 protein ligand 2-(1-benzothiop... 1 0
Coagulation factor X inhibitor SureCN14490781 family 15 0
Coagulation factor X inhibitor SureCN4855529 family 6 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Histone deacetylase 1 inhibitor Benzo[b]thiophene-2-carboxamid... 1 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 5
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN1564756 f... 1 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1
Serine/threonine-protein kinase 33 inhibitor N-[5-fluoro-2-(3-... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434041 CHEMBL309501 Bioactive AGN-PC-074KBT
CFAMM00434040 CHEMBL80875 Bioactive AGN-PC-074KAW

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27527 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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