CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15455
Family Name Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]ethanone family
No. of Seeds 10 No. of Other Members 5
Family Centroid CFAMM00434163 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 Binder Superfamily 4
Class Class 1446

Cousin Family NamesSeedsMembers
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Neuropeptide Y receptor type 5 ligand N-[5-[(9-fluoro-5,6-dihy... 7 7
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Neuropeptide Y receptor type 5 ligand [4-[[(9-fluoro-5,6-dihyd... 3 1
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
5-hydroxytryptamine receptor 2A ligand 4-[(3R)-3-[2-amino-4-(4... 1 0
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-chloro-5,6-dih... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Extracellular calcium-sensing receptor ligand 2-[[3,3-diphenyl... 2 2
Extracellular calcium-sensing receptor ligand 3-(1,3-benzothia... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434156 CHEMBL81104 Bioactive 1-[4-[(5,6-dihydro-4H-benzo[1,2]cyclohepta[3,4-b][1,3]thiazol-2-ylamino)methyl]piperidin-1-yl]-2-piperidin-1-ylethanone
CFAMM00434149 CHEMBL81586 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-morpholin-4-ylethanone
CFAMM00434162 CHEMBL309967 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-(2-methoxyethylamino)ethanone
CFAMM00434155 CHEMBL310674 Bioactive 2-(cyclopropylmethylamino)-1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]ethanone
CFAMM00434161 CHEMBL79663 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-(oxolan-2-ylmethylamino)ethanone
CFAMM00434152 CHEMBL81103 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]ethanone
CFAMM00434158 CHEMBL310670 Bioactive 2-[cyclopropylmethyl(methyl)amino]-1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]ethanone
CFAMM00434157 CHEMBL79308 Bioactive N-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]cyclohexyl]-2-[methyl(propyl)amino]acetamide
CFAMM00434150 CHEMBL82080 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-piperidin-1-ylethanone
CFAMM00434163 CHEMBL421714 Bioactive 2-(dimethylamino)-1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543