CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15467
Family Name Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-methylpropan-1-one family
No. of Seeds 11 No. of Other Members 0
Family Centroid CFAMM00434242 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 Binder Superfamily 4
Class Class 1446

Cousin Family NamesSeedsMembers
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(5-b... 3 9
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Neuropeptide Y receptor type 5 ligand N-[5-(4,5-dihydro-[1]ben... 8 9
Neuropeptide Y receptor type 5 ligand N-[5-[(9-fluoro-5,6-dihy... 7 7
Neuropeptide Y receptor type 5 ligand N-[5-[(4-thiophen-3-yl-1... 1 4
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Neuropeptide Y receptor type 5 ligand [4-[[(9-fluoro-5,6-dihyd... 3 1
Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[... 10 5
5-hydroxytryptamine receptor 2A ligand 4-[(3R)-3-[2-amino-4-(4... 1 0
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-chloro-5,6-dih... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor 4-[[4-(4-carb... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434236 CHEMBL79659 Bioactive N-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]cyclohexyl]pentanamide
CFAMM00434242 CHEMBL81484 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-methylpropan-1-one
CFAMM00434235 CHEMBL84453 Bioactive cyclopropyl-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]methanone
CFAMM00434241 CHEMBL81982 Bioactive N-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]cyclohexyl]cyclopropanecarboxamide
CFAMM00434240 CHEMBL82158 Bioactive methyl N-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]cyclohexyl]carbamate
CFAMM00434239 CHEMBL313454 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-3-methoxypropan-1-one
CFAMM00434247 CHEMBL80003 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]cyclohexyl]pyrrolidin-2-one
CFAMM00434238 CHEMBL310119 Bioactive 2-cyclopropyl-N-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]cyclohexyl]acetamide
CFAMM00434246 CHEMBL83860 Bioactive ethyl 4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidine-1-carboxylate
CFAMM00434237 CHEMBL81994 Bioactive [4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-(oxolan-3-yl)methanone
CFAMM00434244 CHEMBL313087 Bioactive 1-[4-[[(9-fluoro-5,6-dihydro-4H-benzo[2,3]cyclohepta[2,4-b][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]-2-methoxyethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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