CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15472
Family Name Tryptase alpha/beta-1 and Tryptase delta inhibitor [4-[[2-[[4-(aminomethyl)phenyl]methylamino]-2-oxoethyl]carbamoyloxymethyl]phenyl]methyl N-[2-[[4-(aminomethyl)phenyl]methylamino]-2-oxoethyl]carbamate family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00434262 Functional Category Bioactive
Superfamily Renin and Furin Binder Superfamily
Class Class 3206

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cruzipain Inhibitor WRR-204 Family 18 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-nal-agly-ile-v... 3 2
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Cathepsin K inhibitor (4-phenylphenyl) (3S)-3-[[(3S)-1,2-dioxo... 4 10
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Pol polyprotein inhibitor AC1LADQG family 7 1
Melanin-concentrating hormone receptor 1 ligand SureCN7463098 ... 1 0
Protease inhibitor AC1O54RX family 2 4
Pol polyprotein inhibitor AC1LA3C0 family 2 18
C-C chemokine receptor type 5 ligand benzyl N-[1-[(4S)-4-(cycl... 1 0
Cysteine protease inhibitor ethyl (E,4S)-4-[[(2S)-2-[(2-methyl... 2 0
Furin inhibitor benzyl N-[(5S)-6-[[(2S)-1-[[(2S)-1-[(4-carbami... 1 0


External ID

Functional Category

Molecule Name

CFAMM00434262 CHEMBL310290 Bioactive [4-[[2-[[4-(aminomethyl)phenyl]methylamino]-2-oxoethyl]carbamoyloxymethyl]phenyl]methyl N-[2-[[4-(aminomethyl)phenyl]methylamino]-2-oxoethyl]carbamate
CFAMM00434261 CHEMBL80210 Bioactive AGN-PC-074JQJ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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