CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1549
Family Name Prothrombin and Histone-lysine N-methyltransferase 2A inhibitor CHEMBL1350952 family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00324878 Functional Category Bioactive
Superfamily Huntingtin and Prothrombin Binder Superfamily
Class Class 1378

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Aurora kinase A Inhibitor ABT-348 Family 20 49
PF-3758309 family 1 8
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Smoothened homolog inhibitor SureCN1091571 family 2 2
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 12 7
Histamine H3 receptor ligand 2-(3-methyl-[1,2,4]triazolo[4,3-a... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Somatostatin receptor type 1 ligand AGN-PC-078XQI family 1 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 3 0
Glycogen synthase kinase-3 beta inhibitor pyrazolopyrimidine d... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324882 CHEMBL118400 Bioactive pyrazolo[1,5-a]pyrimidine 5c

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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