CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15504
Family Name Retinoic acid receptor beta and Retinoic acid receptor gamma ligand AGN-PC-074JW7 family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00429098 Functional Category Bioactive with Natural Product
Superfamily Nuclear receptor ROR-gamma and Prelamin-A/C Binder Superfamily 25
Class Class 3542

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Fatty acid-binding protein and C-X-C chemokine receptor type 1... 1 6
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Acetylcholinesterase Inhibitor 3-(2,5-dioxo-pyrrolidin-1-yl)-b... 2 4
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Free fatty acid receptor 1 ligand AGN-PC-03ZC6J family 2 14
Sodium-dependent serotonin transporter and D(2) dopamine recep... 8 6
Glucocorticoid receptor ligand 4-[[2-[4-[(8S,11R,13S,14S,17S)-... 6 1
Collagenase 3 inhibitor 4-[[4-oxo-6-(3-phenylprop-1-ynyl)quina... 2 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4
Retinal dehydrogenase 1 and ATP-dependent DNA helicase Q1 inhi... 1 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 1
Glucocorticoid receptor ligand AGN-PC-01X8JJ family 1 0


External ID

Functional Category

Molecule Name

CFAMM00434434 CHEMBL80271 Bioactive 4-[2-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-7-yl)ethynyl]benzoic acid
CFAMM00434437 CHEMBL430616 Bioactive AGN-PC-074JXD

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



48680 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543