CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15516
Family Name Tryptase alpha/beta-1 and Tryptase delta inhibitor SureCN7504794 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00434511 Functional Category Bioactive
Superfamily Furin and Trypsin-1 Binder Superfamily
Class Class 2794

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Motilin receptor Ligand GSK962040 Family 30 457
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 9 19
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 17
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-074J... 8 8
Tryptase gamma and Trypsin-1 inhibitor [(3R,3aR,6R,6aR)-6-[4-[... 1 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-03J1... 4 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Transient receptor potential cation channel subfamily V member... 1 1
Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N... 1 0
Mu-type opioid receptor ligand N-[4-[[(2R)-2-[[[(3S)-3-[(pheny... 1 0


External ID

Functional Category

Molecule Name

CFAMM00434513 CHEMBL76796 Bioactive AGN-PC-074JLD
CFAMM00434511 CHEMBL311655 Bioactive SureCN7504794
CFAMM00434509 CHEMBL76883 Bioactive SureCN7570914
CFAMM00434514 CHEMBL75972 Bioactive AGN-PC-074JLU

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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