CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15521
Family Name Collagenase 3 and Interstitial collagenase inhibitor (4-benzylphenyl)methyl-[2-[[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]carbamoyl]-4-(3-methylphenyl)butyl]phosphinic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00218423 Functional Category Bioactive
Superfamily Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 Superfamily
Class Class 1787

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 F... 3 51
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Endothelin-converting enzyme 1 Inhibitor PO3 2-leu-nal-o-3k Fa... 3 26
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Neprilysin and Aminopeptidase N inhibitor (2S)-2-[[(2S)-2-[[[a... 13 1
Carboxypeptidase B and Carboxypeptidase B2 inhibitor (2S)-7-am... 3 9
Neprilysin inhibitor SureCN489232 family 3 9
Growth factor receptor-bound protein 2 ligand 2-[(9S,10S,11E,1... 5 14
Matrix metalloproteinase-9 inhibitor (3R)-2-[ethoxy-(4-phenylp... 4 15
Growth factor receptor-bound protein 2 ligand [4-[[(2S,5S,9S,1... 2 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 5 3
Neutrophil collagenase and Macrophage metalloelastase inhibito... 1 0
Endothelin-converting enzyme 1 and Neprilysin inhibitor [[(2S)... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434537 CHEMBL77972 Bioactive (4-benzylphenyl)methyl-[4-(4-bromophenyl)-2-[[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]carbamoyl]butyl]phosphinic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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