CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15525
Family Name Mu-type opioid receptor and Delta-type opioid receptor ligand AGN-PC-002JDN family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00434547 Functional Category Bioactive
Superfamily Nociceptin receptor and Mu-type opioid receptor Binder Superfamily 8
Class Class 2396

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Alpha adrenergic receptor Ligand Droperidol Family 20 244
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
E3 ubiquitin-protein ligase Mdm2 inhibitor (2'R,3R,3'S,5'S)-6-... 17 51
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 ligand tert-butyl 4-[(3S)-4-[4-[2-[1-[... 2 6
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Lethal factor inhibitor (2R)-6-[(4-chlorophenyl)methylamino]-2... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 6
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 5 37
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Melanin-concentrating hormone receptor 1 ligand 4-(4-chlorophe... 2 0
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Dipeptidyl peptidase 4 inhibitor SureCN296150 family 3 8
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Growth hormone secretagogue receptor type 1 ligand N-[4,6-dich... 2 0
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Urotensin-2 receptor and Cytochrome P450 2D6 ligand 2-[3,4-dic... 2 3
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Substance-K receptor and Neuromedin-K receptor ligand SureCN78... 2 4
Neuromedin-K receptor and Substance-K receptor ligand AGN-PC-0... 2 2
Mu-type opioid receptor and Nociceptin receptor ligand SureCN8... 7 1
Glutamate receptor ionotropic, NMDA 1 ligand CHEMBL40730 family 4 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Progesterone receptor ligand CHEMBL403139 family 2 0
Nociceptin receptor and Mu-type opioid receptor ligand spiropi... 1 0
C-C chemokine receptor type 1 ligand (2R)-2-N-[(4-chlorophenyl... 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Calcitonin gene-related peptide type 1 receptor and Dual speci... 4 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
Smoothened homolog inhibitor N-(2,6-dichloro-4-cyanophenyl)-1,... 4 3
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 7 1
Aldose reductase inhibitor Spiro-cimqat family 6 8
Aldose reductase inhibitor (4R)-6-fluoro-3-methylspiro[1H-quin... 4 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434546 CHEMBL312046 Bioactive AGN-PC-002JDP
CFAMM00434547 CHEMBL312281 Bioactive AGN-PC-002JDN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26825 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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