CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15532
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0757VU family
No. of Seeds 13 No. of Other Members 39
Family Centroid CFAMM00434627 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 19
Class Class 1715

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Integrin beta-3 Inhibitor Sibrafiban Family 4 6
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Coagulation factor X and Cationic trypsin inhibitor AC1L1JML f... 11 32
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-6-[[2-(4... 2 11
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7301018... 4 3
Integrin beta-3 and Integrin alpha-IIb inhibitor ethyl 2-[1-[3... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor ethyl 2-[1-[3... 1 1
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-074JBK... 1 3
Tryptase alpha/beta-1 inhibitor 4-[[(4-carbamimidoylbenzoyl)am... 1 2


External ID

Functional Category

Molecule Name

CFAMM00434588 CHEMBL78119 Bioactive ethyl 2-[1-[3-[[2-fluoro-4-(4-methylpiperazine-1-carboximidoyl)benzoyl]amino]-2,2-dimethylpentanoyl]piperidin-4-yl]acetate
CFAMM00434627 CHEMBL74908 Bioactive AGN-PC-0757VU
CFAMM00434613 CHEMBL77489 Bioactive ethyl 2-[1-[3-[[2-fluoro-4-(morpholine-4-carboximidoyl)benzoyl]amino]-2,2-dimethylpentanoyl]piperidin-4-yl]acetate
CFAMM00434626 CHEMBL77696 Bioactive ethyl 2-[1-[3-[[2-fluoro-4-(pyrrolidine-1-carboximidoyl)benzoyl]amino]-2,2-dimethylpentanoyl]piperidin-4-yl]acetate
CFAMM00434598 CHEMBL78295 Bioactive 2-[1-[3-[(4-carbamimidoyl-2-fluorobenzoyl)amino]-2,2-dimethylpentanoyl]piperidin-4-yl]acetic acid
CFAMM00434624 CHEMBL432915 Bioactive 2-[1-[3-[(4-carbamimidoylbenzoyl)amino]-2,2-dimethylheptanoyl]piperidin-4-yl]acetic acid
CFAMM00434578 CHEMBL77404 Bioactive AGN-PC-0757SQ
CFAMM00434591 CHEMBL76882 Bioactive ethyl 2-[1-[3-[[2-fluoro-4-(4-hydroxypiperidine-1-carboximidoyl)benzoyl]amino]-2,2-dimethylpentanoyl]piperidin-4-yl]acetate
CFAMM00434584 CHEMBL75645 Bioactive AGN-PC-0757SY
CFAMM00434597 CHEMBL312368 Bioactive AGN-PC-074J5D
CFAMM00434615 CHEMBL76851 Bioactive AGN-PC-0757SP
CFAMM00434595 CHEMBL74553 Bioactive AGN-PC-00GG0Y
CFAMM00434608 CHEMBL77635 Bioactive 2-[1-[3-[(4-carbamimidoyl-2-fluorobenzoyl)amino]-2,2-dimethylbutanoyl]piperidin-4-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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