CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15543
Family Name Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]-1-methylurea family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00434667 Functional Category Bioactive with Natural Product
Superfamily Sodium- and Glutamate receptor ionotropic, NMDA 2B Binder Superfamily
Class Class 3441

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Beta-2 adrenergic receptor Ligand Clenbuterol Family 2 19
Nociceptin receptor Ligand J-113397 Family 3 14
Kinesin-like protein KIF11 Inhibitor EMD-534085 Family 2 26
Mu-type opioid receptor ligand N-[(3S,4R)-1-[(2S)-2-hydroxy-2-... 11 4
Pol polyprotein inhibitor AC1LAMTL family 11 15
Pol polyprotein inhibitor (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bi... 3 2
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
Pol polyprotein inhibitor DMP-450 family 9 4
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 1 5
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 4 9
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[2-[2... 2 1
Malonyl-CoA decarboxylase, mitochondrial inhibitor N-butyl-N-[... 9 5
2-(4-aminophenyl)-2-[[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-m... 2 1
2,6-dimethyl-1,2,3,4-tetrahydroquinolin-4-ol NP (2r,4s)-6-brom... 3 1


External ID

Functional Category

Molecule Name

CFAMM00434664 CHEMBL77770 Bioactive 3-[4-(N-ethylanilino)phenyl]-1-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]-1-methylurea
CFAMM00434667 CHEMBL312739 Bioactive 3-(4-benzylphenyl)-1-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]-1-methylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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