CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15551
Family Name Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family
No. of Seeds 18 No. of Other Members 2
Family Centroid CFAMM00434734 Functional Category Bioactive
Superfamily Tyrosine-protein kinase Lck Binder Superfamily
Class Class 888

Cousin Family NamesSeedsMembers
Abelson tyrosine-protein kinase 2 inhibitor thiazole derivativ... 19 50
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
cAMP-dependent protein kinase catalytic subunit beta and cAMP-... 2 9
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
Thrombopoietin receptor ligand N-[4-[2-fluoro-3-(trifluorometh... 2 14
Tyrosine-protein kinase Lck inhibitor benzothiazole analog 11 ... 7 13
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MPV family 4 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family 4 0
Transient receptor potential cation channel subfamily V member... 9 13
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
D(2) dopamine receptor and Potassium voltage-gated channel sub... 2 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-074FBQ family 2 0


External ID

Functional Category

Molecule Name

CFAMM00434725 CHEMBL313384 Bioactive AGN-PC-074MJS
CFAMM00434731 CHEMBL86392 Bioactive AGN-PC-074MOJ
CFAMM00434737 CHEMBL89562 Bioactive AGN-PC-074MLY
CFAMM00434724 CHEMBL313912 Bioactive AGN-PC-074MPU
CFAMM00434730 CHEMBL84846 Bioactive AGN-PC-074MSR
CFAMM00434736 CHEMBL432189 Bioactive AGN-PC-074MIO
CFAMM00434723 CHEMBL89247 Bioactive AGN-PC-074MUI
CFAMM00434729 CHEMBL89194 Bioactive AGN-PC-074MUH
CFAMM00434735 CHEMBL87604 Bioactive AGN-PC-074ML2
CFAMM00434722 CHEMBL88009 Bioactive AGN-PC-074MHP
CFAMM00434728 CHEMBL87727 Bioactive AGN-PC-074MM4
CFAMM00434734 CHEMBL315778 Bioactive AGN-PC-074MSE
CFAMM00434721 CHEMBL86690 Bioactive AGN-PC-074MUB
CFAMM00434733 CHEMBL313115 Bioactive AGN-PC-074MQV
CFAMM00434720 CHEMBL87102 Bioactive AGN-PC-074MHV
CFAMM00434726 CHEMBL423312 Bioactive AGN-PC-074MT7

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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