CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15556
Family Name Integrin beta-3 and Integrin alpha-V inhibitor SureCN3257002 family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00434755 Functional Category Bioactive with Natural Product
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 19
Class Class 1455

Cousin Family NamesSeedsMembers
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3256223 f... 7 1
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-5-oxo-5-[4... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00434758 CHEMBL431208 Bioactive (2S)-5-[4-[3-[(5,5-dimethyl-4,6-dihydro-1H-pyrimidin-2-yl)amino]phenyl]piperazin-1-yl]-2-(2-methylpropoxycarbonylamino)-5-oxopentanoic acid
CFAMM00434751 CHEMBL85196 Bioactive (2S)-5-oxo-2-[(2-phenylacetyl)amino]-5-[4-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]piperazin-1-yl]pentanoic acid
CFAMM00434757 CHEMBL313045 Bioactive (2S)-2-(ethylcarbamoylamino)-5-oxo-5-[4-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]piperazin-1-yl]pentanoic acid
CFAMM00434750 CHEMBL315956 Bioactive (2S)-2-(benzylcarbamoylamino)-5-oxo-5-[4-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]piperazin-1-yl]pentanoic acid
CFAMM00434756 CHEMBL84911 Bioactive (2S)-2-(ethoxycarbonylamino)-5-oxo-5-[4-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]piperazin-1-yl]pentanoic acid
CFAMM00434755 CHEMBL84683 Bioactive SureCN3257002
CFAMM00434761 CHEMBL87372 Bioactive SureCN3253692
CFAMM00434760 CHEMBL407984 Bioactive (2S)-5-[4-[3-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]phenyl]piperazin-1-yl]-2-(2-methylpropoxycarbonylamino)-5-oxopentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48689 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543