CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15565
Family Name Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ligand 3-[2-[4-[1-(4-fluorophenyl)-5-(1-methyl-1,2,4-triazol-3-yl)indol-3-yl]piperidin-1-yl]ethyl]-1,3-oxazolidin-2-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00162318 Functional Category Bioactive
Superfamily Tedizolid Superfamily
Class Class 1331

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
HER Inhibitor AC480 Family 4 67
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
Tedizolid family 2 2
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-2 angiotensin II receptor Ligand SC-55634 Family 8 5
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 14 4
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 7 3
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Histamine H3 receptor ligand SureCN4025673 family 4 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
Serine/threonine-protein kinase B-raf inhibitor SureCN3495787 ... 8 1
Serine/threonine-protein kinase B-raf inhibitor SureCN1013857 ... 9 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Survival motor neuron protein and Menin inhibitor CHEMBL132797... 1 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Cholecystokinin receptor type A ligand 6-[2-[2-(cyclohexylmeth... 2 6
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Casein kinase II subunit alpha and Homeodomain-interacting pro... 5 0
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
Growth hormone secretagogue receptor type 1 ligand SureCN36660... 4 14
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 1 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-[(1-... 9 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 0
Somatostatin receptor type 1 ligand AGN-PC-078XQI family 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 9 0
Metabotropic glutamate receptor 5 ligand 2-[4-(4-fluoro-3-meth... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24517 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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