CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15585
Family Name Type-1A angiotensin II receptor and Type-1B angiotensin II receptor ligand AGN-PC-006WAV family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00075000 Functional Category Bioactive
Superfamily Casein kinase II, alpha chain Inhibitor CGP-029482 Superfamily
Class Class 1253

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... 2 1
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Adenosine receptor A1 ligand AGN-PC-07PMLW family 6 4
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Prostaglandin D2 receptor 2 ligand SureCN2215286 family 7 5
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
C-C chemokine receptor type 5 ligand SureCN13543564 family 10 3
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 3 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 3
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Type-1A angiotensin II receptor ligand 2-[4-[[2-butyl-5-(tert-... 1 0
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Type-1B angiotensin II receptor ligand SureCN9310003 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435002 CHEMBL87327 Bioactive AGN-PC-074MCT
CFAMM00435001 CHEMBL314315 Bioactive 2-chloro-4-[4-[(5,7-dimethyl-2-propylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]quinoline-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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