CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15591
Family Name Sodium-dependent dopamine transporter and Sigma non-opioid intracellular receptor 1 ligand (2S)-1-[4-[3-(4-fluoro-N-(4-fluorophenyl)anilino)propyl]piperazin-1-yl]-3-phenylpropan-2-ol family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00435036 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 and Bloom syndrome protein Binder Superfamily
Class Class 4259

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand Sonepiprazole Family 2 6
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 29
Mu-type opioid receptor ligand N-[(3S,4R)-1-[(2S)-2-hydroxy-2-... 11 4
Bloom syndrome protein and Cytochrome P450 3A4 inhibitor CHEMB... 1 3
Sodium-dependent dopamine transporter and Transporter inhibito... 1 6
D(1A) dopamine receptor and D(3) dopamine receptor ligand 4-[(... 2 3
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
Sodium-dependent dopamine transporter and Sigma non-opioid int... 5 8
Sodium-dependent dopamine transporter and Sigma non-opioid int... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 1 7
D(1A) dopamine receptor and D(3) dopamine receptor ligand Sure... 1 0


External ID

Functional Category

Molecule Name

CFAMM00435036 CHEMBL495519 Bioactive (2S)-1-[4-[3-(4-fluoro-N-(4-fluorophenyl)anilino)propyl]piperazin-1-yl]-3-phenylpropan-2-ol
CFAMM00435029 CHEMBL495520 Bioactive (2R)-1-[4-[3-(4-fluoro-N-(4-fluorophenyl)anilino)propyl]piperazin-1-yl]-3-phenylpropan-2-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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