CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15595
Family Name Estrogen receptor beta and Estrogen receptor ligand AGN-PC-074LJC family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00435058 Functional Category Bioactive
Superfamily Oestrogen receptor Ligand Raloxifene Superfamily
Class Class 453

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Oestrogen receptor Ligand Raloxifene Family 4 169
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Ipriflavone family 62 2480
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Celivarone family 1 1
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Oestrogen receptor and Tyrosine-protein phosphatase non-recept... 92 21
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Histamine H3 receptor Ligand A-349821 Family 49 228
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 3 0
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 0
Estrogen receptor and Estrogen receptor beta ligand SureCN7103... 1 1
Histamine H1 receptor ligand Ahr 5333 family 1 6
Histamine H3 receptor ligand SureCN2784769 family 12 2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and Sigma no... 2 4
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 3 0
Estrogen receptor and Estrogen receptor beta ligand SureCN1450... 1 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 1
ALK tyrosine kinase receptor ligand SureCN898429 family 3 0
Multidrug resistance protein 1 inhibitor 1-[4-[(2R)-2-hydroxy-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00435058 CHEMBL315474 Bioactive AGN-PC-074LJC
CFAMM00435056 CHEMBL432371 Bioactive AGN-PC-074LJZ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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