CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1560
Family Name Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ligand AGN-PC-00GZNF family
No. of Seeds 15 No. of Other Members 14
Family Centroid CFAMM00325067 Functional Category Bioactive
Superfamily Beta-lactamase and Mu-type opioid receptor Binder Superfamily
Class Class 2780

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325067 CHEMBL302268 Bioactive AGN-PC-00GZNF
CFAMM00325080 CHEMBL68447 Bioactive 4-chloro-2-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-5-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325073 CHEMBL118704 Bioactive 5-chloro-2-[7-[4-(2-ethoxyphenyl)piperazin-1-yl]heptyl]-4-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325086 CHEMBL66965 Bioactive 2-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-6-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325066 CHEMBL47792 Bioactive 4-chloro-5-[4-(furan-2-carbonyl)piperazin-1-yl]-2-[7-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]heptyl]pyridazin-3-one
CFAMM00325079 CHEMBL65963 Bioactive 4-chloro-2-[5-[4-(2-chlorophenyl)piperazin-1-yl]pentyl]-5-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325059 CHEMBL46172 Bioactive 4-chloro-5-[4-(furan-2-carbonyl)piperazin-1-yl]-2-[7-[4-(2-methoxyphenyl)piperazin-1-yl]heptyl]pyridazin-3-one
CFAMM00325085 CHEMBL118770 Bioactive 5-chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]-2-[7-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]heptyl]pyridazin-3-one
CFAMM00325058 CHEMBL67379 Bioactive 4-chloro-2-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]-5-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325071 CHEMBL118661 Bioactive 5-chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]-2-[7-[4-(2-methoxyphenyl)piperazin-1-yl]heptyl]pyridazin-3-one
CFAMM00325070 CHEMBL67201 Bioactive 4-chloro-5-[4-(furan-2-carbonyl)piperazin-1-yl]-2-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]pyridazin-3-one
CFAMM00325063 CHEMBL45726 Bioactive AGN-PC-073QLG
CFAMM00325069 CHEMBL302857 Bioactive 2-[7-[4-(2-chlorophenyl)piperazin-1-yl]heptyl]-6-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325075 CHEMBL66272 Bioactive 4-chloro-2-[3-[4-(2-chlorophenyl)piperazin-1-yl]propyl]-5-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one
CFAMM00325068 CHEMBL417745 Bioactive 2-[4-[4-(2-chlorophenyl)piperazin-1-yl]butyl]-6-[4-(furan-2-carbonyl)piperazin-1-yl]pyridazin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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