CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15611
Family Name Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma and Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha inhibitor 8-[5-(4-ethylpiperazin-1-yl)sulfonyl-2-propoxyphenyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00435215 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2b Binder Superfamily
Class Class 253

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Vardena... 3 39
Adenosine receptor A2a Ligand KW-6002 Family 18 195
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 3 0
Adenosine receptor A2b ligand 2-[5-(2,6-dioxo-1,3-dipropyl-7H-... 1 0
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Adenosine receptor A1 and Adenosine receptor A2b ligand (4-nit... 8 2
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
Adenosine receptor A2b and Adenosine receptor A2a ligand 1-eth... 5 2
Adenosine receptor A1 and Adenosine receptor A2b ligand N-[2-[... 2 1
P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435215 CHEMBL315477 Bioactive 8-[5-(4-ethylpiperazin-1-yl)sulfonyl-2-propoxyphenyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
CFAMM00435214 CHEMBL87202 Bioactive 1-methyl-8-[5-(4-methylpiperazin-1-yl)sulfonyl-2-propoxyphenyl]-3-(2-methylpropyl)-7H-purine-2,6-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26823 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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