Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
CFAM Family ID CFFBM15612
Family Name Renin and Cathepsin E inhibitor (2S)-N-[(2S,3S,5R)-1-cyclohexyl-3,5-dihydroxyheptan-2-yl]-3-(4H-imidazol-4-yl)-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]propanamide family
No. of Seeds 1
No. of Other Members 0
CFAMM00235078 Functional Category Bioactive
Superfamily Renin and Cathepsin E Binder Superfamily
Class Class 1444
Cousin Family Names Seeds Members Renin Inhibitor CP-80794 Family 16 112 Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131 Beta-secretase 1 Inhibitor MMI-175 Family 30 137 Plasmepsin-1 Inhibitor SC-5003 Family 93 173 Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1 Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2 Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1 Renin inhibitor N-[(3S)-5-[2-(2-aminoethyl)morpholin-4-yl]-1-c... 4 2 Cathepsin E and Renin inhibitor (2S)-N-[2-[[(2S,3S,5S)-1-cyclo... 4 0 Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 15 0 Renin and Cathepsin D inhibitor ethyl (4S)-5-cyclohexyl-2,2-di... 2 0 72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 10 0 Renin inhibitor 2-methylpropyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl... 14 0 Renin inhibitor ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-d... 2 0
CFAM Mol ID
Statistics of CFAM Database
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
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