CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15628
Family Name Tyrosine-protein kinase Lck inhibitor AGN-PC-074MPV family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00435265 Functional Category Bioactive
Superfamily Tyrosine-protein kinase Lck Binder Superfamily
Class Class 888

Cousin Family NamesSeedsMembers
Abelson tyrosine-protein kinase 2 inhibitor thiazole derivativ... 19 50
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
Tyrosine-protein kinase Lck inhibitor benzothiazole analog 11 ... 7 13
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435265 CHEMBL87917 Bioactive AGN-PC-074MPV
CFAMM00435268 CHEMBL86939 Bioactive AGN-PC-074MWT
CFAMM00435267 CHEMBL315643 Bioactive AGN-PC-074MK5
CFAMM00435266 CHEMBL86338 Bioactive AGN-PC-074MOI

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26400 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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