CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15629
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand (3E)-3-imidazo[4,5-c]quinolin-2-ylidene-1,2-oxazole family
No. of Seeds 11 No. of Other Members 4
Family Centroid CFAMM00435272 Functional Category Bioactive
Superfamily Aurora kinase A and GABA theta subunit Binder Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 10 23
Aurora kinase A and Potassium voltage-gated channel subfamily ... 8 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 1
Neuronal acetylcholine receptor subunit alpha-4 ligand AGN-PC-... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


External ID

Functional Category

Molecule Name

CFAMM00435270 CHEMBL321971 Bioactive (3E)-3-(7-chloroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole
CFAMM00435279 CHEMBL95673 Bioactive (3E)-3-(8-chloroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole
CFAMM00435277 CHEMBL317342 Bioactive (3E)-3-(8-fluoroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole
CFAMM00435269 CHEMBL95471 Bioactive (3E)-3-(7-fluoroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole
CFAMM00435284 CHEMBL97260 Bioactive CHEMBL97260
CFAMM00435275 CHEMBL97442 Bioactive (3E)-3-imidazo[4,5-c]quinolin-2-ylidene-5-methyl-1,2-oxazole
CFAMM00435283 CHEMBL95900 Bioactive (3E)-5-ethyl-3-imidazo[4,5-c]quinolin-2-ylidene-1,2-oxazole
CFAMM00435282 CHEMBL441639 Bioactive (3E)-3-(9-fluoroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole
CFAMM00435273 CHEMBL99458 Bioactive CHEMBL99458
CFAMM00435281 CHEMBL316964 Bioactive (3E)-3-(6,7,8,9-tetrahydroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole
CFAMM00435280 CHEMBL315648 Bioactive (3E)-3-(9-chloroimidazo[4,5-c]quinolin-2-ylidene)-1,2-oxazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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