CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15646
Family Name Pol polyprotein inhibitor Enantiomer of AG1284 family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00435331 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 45
Class Class 5131

Cousin Family NamesSeedsMembers
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Beta-secretase 1 inhibitor SureCN8292705 family 7 6
Beta-secretase 1 inhibitor N-[(1S,2S)-1-[(2R)-4-benzylsulfonyl... 2 0
Pol polyprotein inhibitor 2-[(2R,3S)-3-[[(2R)-3-(benzenesulfin... 15 15
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 13
Pol polyprotein inhibitor 152928-55-7 family 23 2
Pol polyprotein inhibitor AC1LALX3 family 2 0
Pol polyprotein inhibitor 3-[(4R,5R,6R)-4-benzyl-3-(3-carbamoy... 3 1
Pol polyprotein inhibitor 3-[[(3S,5R)-5-benzyl-1-[(2S,4R)-4-be... 4 0
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Beta-secretase 1 inhibitor 1-N-[(1R,2S)-1-[(2R,4S)-4-butoxypip... 5 1
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Pol polyprotein inhibitor AC1LAMTC family 6 0
Substance-P receptor ligand AGN-PC-03I9DJ family 3 0
Pol polyprotein inhibitor AC1LALY0 family 1 5
Pol polyprotein inhibitor diarylbutanol deriv. 13 family 1 0
Pol polyprotein inhibitor Tertiary Amide deriv. 56 family 1 0
Muscarinic acetylcholine receptor M3 ligand N-[[4-fluoro-3-[3-... 3 0


External ID

Functional Category

Molecule Name

CFAMM00435334 CHEMBL330730 Bioactive AC1LA3JU
CFAMM00435333 CHEMBL316480 Bioactive AC1LA3JR
CFAMM00435332 CHEMBL327566 Bioactive AC1LA3JF
CFAMM00435331 CHEMBL328435 Bioactive Enantiomer of AG1284
CFAMM00435337 CHEMBL94995 Bioactive AC1LA3JI
CFAMM00435330 CHEMBL347662 Bioactive AC1LALEP
CFAMM00435335 CHEMBL97487 Bioactive Tertiary Amide deriv. 49

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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