CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1565
Family Name Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ligand AGN-PC-00F27Q family
No. of Seeds 7 No. of Other Members 13
Family Centroid CFAMM00325131 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor Binder Superfamily
Class Class 2246

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 5
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 5 3


External ID

Functional Category

Molecule Name

CFAMM00325121 CHEMBL123871 Bioactive 6-imidazol-1-yl-2-[7-[4-(2-methoxyphenyl)piperazin-1-yl]heptyl]pyridazin-3-one
CFAMM00325120 CHEMBL123870 Bioactive 6-(benzimidazol-1-yl)-2-[7-[4-(2-methoxyphenyl)piperazin-1-yl]heptyl]pyridazin-3-one
CFAMM00325135 CHEMBL120455 Bioactive 6-(benzimidazol-1-yl)-2-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyridazin-3-one
CFAMM00325133 CHEMBL334015 Bioactive 6-(benzimidazol-1-yl)-2-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]pyridazin-3-one
CFAMM00325138 CHEMBL121894 Bioactive 6-(benzimidazol-1-yl)-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyridazin-3-one
CFAMM00325131 CHEMBL118764 Bioactive AGN-PC-00F27Q
CFAMM00325137 CHEMBL523774 Bioactive AGN-PC-050CDM

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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