CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15653
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand (7S)-7-(dipropylamino)-5,6,7,8-tetrahydroindolizine-3-carbaldehyde family
No. of Seeds 2 No. of Other Members 19
Family Centroid CFAMM00435372 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily D(3) dopamine receptor and D(2) dopamine receptor ligand (7S)-7-(dipropylamino)-5,6,7,8-tetrahydroindolizine-3-carbaldehyde Superfamily
Class Class 2019

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Tubulin Inhibitor E 7974 Family 1 7
Substance-P receptor Ligand TAK-637 Family 18 63
Brostallicin family 3 4
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Dual specificity mitogen-activated protein kinase kinase 1 Inh... 2 7
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
M-phase inducer phosphatase 2 Inhibitor 6,7-dibromoquinoline-5... 1 2
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... 12 46
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... 2 3
Aldose reductase Inhibitor 3-(3-benzoyl-1h-pyrrol-1-yl)propano... 3 7
Histamine H3 receptor ligand SureCN1857507 family 1 4
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 12
Serine/threonine-protein kinase PLK1 and MAP kinase-activated ... 1 2
Melanin-concentrating hormone receptor 1 ligand N-[(3S)-1-[[(3... 2 0
Dipeptidyl peptidase 4 inhibitor SureCN5777667 family 1 4
Tyrosyl-DNA phosphodiesterase 1 and Huntingtin inhibitor CHEMB... 1 8
Histone deacetylase 6 and Histone deacetylase 8 inhibitor N-hy... 1 0
Aldose reductase inhibitor 2'-methylspiro[pyrrolidine-3,4'-pyr... 2 0
D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 1 1
Pyridines and Derivatives Metabolite 2-Acetyl-6-methylpyridine... 1 2
Naphthyridines Metabolite 3-Acetyl-2,7-naphthyridine Family 1 4
NP 1-((tetrahydrofuran-2-yl)methyl)-1h-pyrrole-2-carbaldehyde ... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435380 CHEMBL365987 Bioactive AGN-PC-006ZKS
CFAMM00435372 CHEMBL316983 Bioactive (7S)-7-(dipropylamino)-5,6,7,8-tetrahydroindolizine-3-carbaldehyde

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543