CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15660
Family Name Squalene synthase inhibitor 3-[2-(4-phenylphenyl)ethynyl]-1-azabicyclo[2.2.2]octan-3-ol family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00435408 Functional Category Bioactive
Superfamily Squalene synthase and Histamine H3 receptor Binder Superfamily 2
Class Class 3557

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Terfenadine Family 3 50
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and D(2) dopamine receptor Ligand (+)-bu... 5 14
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Histamine H3 receptor ligand SureCN5551955 family 2 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 3
Vesicular acetylcholine transporter inhibitor 2-Naphthalenol, ... 3 2
Vesicular acetylcholine transporter inhibitor (1R,2R)-2-spiro[... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435408 CHEMBL317462 Bioactive 3-[2-(4-phenylphenyl)ethynyl]-1-azabicyclo[2.2.2]octan-3-ol
CFAMM00435410 CHEMBL322662 Bioactive AGN-PC-023EZB

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27069 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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