CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15661
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand (5E)-5-(8-methoxyimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00435411 Functional Category Bioactive
Superfamily GABA theta subunit and Histamine H3 receptor Binder Superfamily
Class Class 1877

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 3
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 10 23
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
Melatonin receptor type 1A ligand N-[2-(5-methoxy-2-phenyl-1H-... 1 2
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 8 6
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Vascular endothelial growth factor receptor 2 and Platelet-der... 16 11
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-[5-(diflu... 7 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-04... 8 1
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 11 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 1
Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 15 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435413 CHEMBL97814 Bioactive (5E)-5-(7-methoxyimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole
CFAMM00435412 CHEMBL317513 Bioactive CHEMBL317513
CFAMM00435411 CHEMBL329930 Bioactive (5E)-5-(8-methoxyimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27265 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543