CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1568
Family Name Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor S-(3-pyridin-3-ylpropyl) (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carbothioate family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00325150 Functional Category Bioactive
Superfamily Voltage-dependent N-type calcium channel subunit alpha-1B and Prelamin-A/C Binder Superfamily
Class Class 64

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
FK506-binding protein 1A Inhibitor Gpi-1046 Family 4 10
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Prolyl endopeptidase inhibitor [(2S,3aS,7aS)-2-(pyrrole-1-carb... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
Platelet-activating factor receptor ligand YM-461 family 1 11
Seprase and Prolyl endopeptidase inhibitor [(2R)-1-[(2R)-2-[(2... 4 2
Neutrophil elastase inhibitor N-[(2S)-3-methyl-1-oxo-1-[(2S)-2... 4 4
Survival motor neuron protein and Microtubule-associated prote... 1 0
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 5 0
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325150 CHEMBL118858 Bioactive S-(3-pyridin-3-ylpropyl) (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carbothioate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543