CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15682
Family Name 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor ligand 6-fluoro-8-[2-[4-(4-methoxyphenyl)butylamino]ethoxy]-2,3-dihydrochromen-4-one family
No. of Seeds 5 No. of Other Members 5
Family Centroid CFAMM00043559 Functional Category Bioactive
Superfamily Acetylcholinesterase Inhibitor Taspine Superfamily
Class Class 2572

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
Rotenone family 16 107
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 18
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Histamine H1 receptor ligand Ahr 5333 family 1 6
Potassium voltage-gated channel subfamily H member 2 and Melan... 4 22
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 7
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 10 8
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Histamine H1 receptor and Cysteinyl leukotriene receptor 1 lig... 1 15
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 1
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
2-[4-(6-methoxy-2-oxochromen-3-yl)phenoxy]acetamide NP (s)-n-(... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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