CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15683
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor SureCN9033274 family
No. of Seeds 18 No. of Other Members 39
Family Centroid CFAMM00435524 Functional Category Bioactive
Superfamily Substance-P receptor and Leukotriene B4 receptor 1 Binder Superfamily
Class Class 2449

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Histamine H1 receptor and Histamine H2 receptor ligand SureCN6... 1 3


External ID

Functional Category

Molecule Name

CFAMM00435524 CHEMBL97506 Bioactive SureCN9033274
CFAMM00435517 CHEMBL98478 Bioactive SureCN9032946
CFAMM00435556 CHEMBL421752 Bioactive SureCN9466289
CFAMM00435536 CHEMBL319505 Bioactive SureCN9033071
CFAMM00435555 CHEMBL95410 Bioactive SureCN9465300
CFAMM00435561 CHEMBL96030 Bioactive 4-[2-[[(E)-3-[1-(2-methylhexan-3-yl)indol-5-yl]but-2-enoyl]amino]phenoxy]butanoic acid
CFAMM00435535 CHEMBL319506 Bioactive SureCN9034563
CFAMM00435534 CHEMBL99860 Bioactive SureCN9032417
CFAMM00435547 CHEMBL95843 Bioactive SureCN9033778
CFAMM00435520 CHEMBL99514 Bioactive SureCN9033081
CFAMM00435546 CHEMBL329690 Bioactive SureCN9033689
CFAMM00435559 CHEMBL99811 Bioactive SureCN9033561
CFAMM00435526 CHEMBL318512 Bioactive SureCN9031579
CFAMM00435552 CHEMBL431270 Bioactive SureCN9032821
CFAMM00435532 CHEMBL99824 Bioactive SureCN9465719
CFAMM00435545 CHEMBL330421 Bioactive SureCN9032622
CFAMM00435525 CHEMBL95403 Bioactive SureCN9034089
CFAMM00435538 CHEMBL319549 Bioactive SureCN9033573

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



70843 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543