CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15690
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand (5E)-5-imidazo[4,5-c]quinolin-2-ylidene-3-methyl-2H-1,2-oxazole family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00435602 Functional Category Bioactive
Superfamily Aurora kinase A and GABA theta subunit Binder Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 10 23
Aurora kinase A and Potassium voltage-gated channel subfamily ... 8 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 11 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 0
Neuronal acetylcholine receptor subunit alpha-4 ligand AGN-PC-... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


External ID

Functional Category

Molecule Name

CFAMM00435608 CHEMBL97365 Bioactive (5E)-5-(9-fluoroimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole
CFAMM00435600 CHEMBL95451 Bioactive (5E)-5-(7-fluoroimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole
CFAMM00435607 CHEMBL99722 Bioactive (5E)-5-(8-fluoroimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole
CFAMM00435606 CHEMBL99255 Bioactive (5E)-5-(8-chloroimidazo[4,5-c]quinolin-2-ylidene)-3-methyl-2H-1,2-oxazole
CFAMM00435605 CHEMBL318722 Bioactive (5E)-3-ethyl-5-imidazo[4,5-c]quinolin-2-ylidene-2H-1,2-oxazole
CFAMM00435604 CHEMBL319082 Bioactive (5E)-3-methyl-5-(6,7,8,9-tetrahydroimidazo[4,5-c]quinolin-2-ylidene)-2H-1,2-oxazole
CFAMM00435602 CHEMBL93613 Bioactive (5E)-5-imidazo[4,5-c]quinolin-2-ylidene-3-methyl-2H-1,2-oxazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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