CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM157
Family Name Prothrombin inhibitor 2-[6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-oxopyrazin-1-yl]-N-[[2-(2-methyltetrazol-5-yl)phenyl]methyl]acetamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00308191 Functional Category Bioactive
Superfamily Adenosine receptor A2b Ligand CVT-7124 Superfamily
Class Class 1286

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Prothrombin inhibitor SureCN5855598 family 4 2
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Prothrombin inhibitor SureCN5855286 family 15 8
Prothrombin inhibitor SureCN7371121 family 13 3
Prothrombin inhibitor SureCN5854779 family 4 9
Prothrombin inhibitor SureCN5856722 family 3 16
Prothrombin and Trypsin-1 inhibitor SureCN12636557 family 9 1
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
Prothrombin inhibitor AGN-PC-09QKE4 family 1 0
Neuropeptide Y receptor type 5 ligand (5E)-5-[(4S,5S)-4-(4-flu... 18 3
Prothrombin inhibitor AGN-PC-073GVF family 12 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308192 CHEMBL102971 Bioactive 2-[6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-oxopyrazin-1-yl]-N-[[2-(1-methyltetrazol-5-yl)phenyl]methyl]acetamide
CFAMM00308191 CHEMBL105909 Bioactive 2-[6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-oxopyrazin-1-yl]-N-[[2-(2-methyltetrazol-5-yl)phenyl]methyl]acetamide
CFAMM00308190 CHEMBL319022 Bioactive AGN-PC-004RDA
CFAMM00308189 CHEMBL321141 Bioactive SureCN5855218
CFAMM00308187 CHEMBL317915 Bioactive SureCN5856819

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27624 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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