CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1570
Family Name D(2) dopamine receptor and D(3) dopamine receptor ligand 8-chloro-6-(4-ethylpiperazin-1-yl)-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00325158 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 12
Class Class 1800

Cousin Family NamesSeedsMembers
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 8
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 1
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 3 7
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 8 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325157 CHEMBL2111781 Bioactive (6R)-8-chloro-6-(4-methylpiperazin-1-yl)-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine
CFAMM00325162 CHEMBL120512 Bioactive SureCN3285765
CFAMM00325161 CHEMBL368324 Bioactive (6S)-8-chloro-6-(4-methylpiperazin-1-yl)-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine
CFAMM00325159 CHEMBL177455 Bioactive AGN-PC-00EXR7
CFAMM00325165 CHEMBL426763 Bioactive SureCN6208140
CFAMM00325158 CHEMBL118889 Bioactive 8-chloro-6-(4-ethylpiperazin-1-yl)-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

40650 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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