CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15703
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-benzodioxol-5-yl)-3-[[(3R)-5-oxo-1-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]pyrrolidine-3-carbonyl]amino]propanoic acid family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00435661 Functional Category Bioactive
Superfamily Genome polyprotein Inhibitor Azapeptide Derivative Superfamily
Class Class 954

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Endothelin B receptor and Endothelin-1 receptor ligand SureCN8... 6 4
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[6-[[... 2 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Coagulation factor VII and Prothrombin inhibitor (S)-[(R)-2-(4... 2 8
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-075FY0 f... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 22
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 12 13
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Angiotensin-converting enzyme inhibitor 2-[[(2S)-6-amino-2-[hy... 2 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435660 CHEMBL98776 Bioactive AGN-PC-074RYX
CFAMM00435659 CHEMBL99709 Bioactive AGN-PC-074S2I
CFAMM00435658 CHEMBL99667 Bioactive 3-(1,3-benzodioxol-5-yl)-3-[[1-[2-fluoro-5-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]-5-oxopyrrolidine-3-carbonyl]amino]propanoic acid
CFAMM00435657 CHEMBL431224 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-3-[[(3R)-5-oxo-1-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]pyrrolidine-3-carbonyl]amino]propanoic acid
CFAMM00435661 CHEMBL318915 Bioactive (3R)-3-(1,3-benzodioxol-5-yl)-3-[[(3R)-5-oxo-1-[3-(1,4,5,6-tetrahydropyrimidin-2-ylamino)phenyl]pyrrolidine-3-carbonyl]amino]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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