CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15717
Family Name Type-1A angiotensin II receptor and Type-1B angiotensin II receptor ligand methyl 2-[2-butyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]-6-methyl-1-oxidopyridin-1-ium-3-carboxylate family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00435703 Functional Category Bioactive
Superfamily Cytochrome P450 2D6 and Tyrosine-protein kinase SYK Binder Superfamily
Class Class 307

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Platelet-activating factor receptor ligand SureCN7497229 family 4 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 6
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Mitogen-activated protein kinase 14 inhibitor methyl 4-[5-(eth... 3 11
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Type-1 angiotensin II receptor ligand 2-propyl-3-[[4-[2-(2H-te... 3 0
Mitogen-activated protein kinase 14 inhibitor ethyl 4-[5-[(3-f... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Platelet-activating factor receptor ligand SureCN7494441 family 1 1
Platelet-activating factor receptor ligand SureCN7497807 family 1 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435701 CHEMBL319990 Bioactive methyl 2-[2-butyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]-4,6-dimethyl-1-oxidopyridin-1-ium-3-carboxylate
CFAMM00435703 CHEMBL98592 Bioactive methyl 2-[2-butyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]-6-methyl-1-oxidopyridin-1-ium-3-carboxylate
CFAMM00435702 CHEMBL98370 Bioactive methyl 6-[2-butyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]pyridazine-3-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43018 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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